This tutorial demonstrates how to add the reference of a known article into your EndNote library via the PubMed connection file from within EndNote. Again, this is best if you have a stack of known articles and need to quickly enter their references into EndNote. This is not recommended if you do not have known articles and need to do subject searches. In that case, you can do your searches in PubMed directly and import the search results into EndNote. This tutorial uses EndNote X4 in the demo.