The Living Textbook of Pragmatic Clinical Trials is a collection of knowledge from the NIH Health Care Systems Research Collaboratory. This free web-accessed resource reflects a collection of special considerations and best practices in the design, conduct, and reporting of pragmatic clinical trials and is organized to follow the linear progression of these stages.
Within this resource, special attention is nowgiven to the utilization and redistribution of research data by having dedicated sections on:
Assessing fitness for use of real-world data sources (i.e., determining the applicability, quality and provenance of a dataset)
As of January 2021, the Living Textbook added information on using claims and CMS files. See the announcement and a list of added topics here. Other data types covered include, electronic health records (EHRs), administrative claims, patient-reported outcomes (PROs), patient-generated health data (PGHD), medical product/device registries, condition-specific or disease registries, and environmental factors / social determinants of health.
Learn more about these topics, and additional topics covered by the NIH Collaboratory Living Textbook of Pragmatic Clinical Trials by utilizing this textbook here.