James E. Rothman, ’71 B.S., the Fergus F. Wallace Professor of Biomedical Sciences, and professor and chair of the Department of Cell Biology at Yale University, was awarded the 2013 Nobel Prize in Physiology or Medicine for his work on how molecular messages are transmitted inside and outside of our cells, the Royal Swedish National Academy announced today (Oct.7). Rothman, who is also professor of chemistry at Yale, shares the prize with Randy Schekman of the University of California, Berkeley and Thomas Südhof of Stanford University.
See the YaleNews item for more information on James Rothman and his research.
To learn more about Rothman’s research and to see the impact of his scientific discoveries, follow the articles links below:
Sollner, T., Whiteheart, S. W., Brunner, M., Erdjument-Bromage, H., Geromanos, S., Tempst, P., & Rothman, J. E. (1993). SNAP receptors implicated in vesicle targeting and fusion. Nature, 362(6418), 318-324. Cited 1745 times in Scopus. http://dx.doi.org/10.1038/362318a0
Rothman, J. E. (1994). Mechanisms of intracellular protein transport. Nature, 372(6501), 55-63. Cited 1671 times in Scopus. http://dx.doi.org/10.1038/372055a0
Weber, T., Zemelman, B. V., McNew, J. A., Westermann, B., Gmachl, M., Parlati, F.,Rothman, J. E. (1998). SNAREpins: Minimal machinery for membrane fusion. Cell, 92(6), 759-772. Cited 1430 times in Scopus. http://dx.doi.org/10.1016/S0092-8674(00)81404-X
Sollner, T., Bennett, M. K., Whiteheart, S. W., Scheller, R. H., & Rothman, J. E. (1993). A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell, 75(3), 409-418. Cited 1065 times in Scopus. http://dx.doi.org/10.1016/0092-8674(93)90376-2
Miesenbock, G., De Angelis, D. A., & Rothman, J. E. (1998). Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature, 394(6689), 192-195. Cited 946 times in Scopus. http://dx.doi.org/10.1038/28190
Rothman, J. E., & Wieland, F. T. (1996). Protein sorting by transport vesicles. Science, 272(5259), 227-234. Cited 898 times in Scopus. http://dx.doi.org/10.1126/science.272.5259.227