This series of tutorials cover the fundamental concepts and general procedure of searching the health science literature in a systematic manner. They will mainly focus on systematic searches required by a "systematic review". The goal of these tutorials is to ensure that your search is comprehensive, methodical, transparent and reproducible, so that your conclusions are as unbiased and closer to truth as possible. This first video of the series introduces the concept of "systematic review" and makes a rough comparison between a search done for a systematic review and an ordinary literature search.