Science Classic provides access to the digitized full text archives of Science from its first issue in 1880 through 1996. Key articles in the history of science from the late 19th through the early 21st centuries are now at your fingertips. The full-text articles available in the Science Classic archive are available in high resolution PDF format. References are available in HTML and dynamically linked to the full text when available.
Lynn Sette's blog
Clinical Alert: Commonly Used Three-drug Regimen for Idiopathic Pulmonary Fibrosis Found Harmful NIH Stops One Treatment Arm of Trial; Other Two Treatments to Continue The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns. The trial found that people with IPF receiving a currently used triple-drug therapy consisting of prednisone, azathioprine, and N-acetylcysteine (NAC) had worse outcomes than those who received placebos or inactive substances. "These findings underscore why treatments must be evaluated in a rigorous manner," said Susan B. Shurin, M.D., acting director of the NHLBI. "This combination therapy is widely used in patients with IPF, but has not previously been studied in direct comparison to a placebo for all three drugs." The interim results from this study showed that compared to placebo, those assigned to triple therapy had greater mortality (11 percent versus 1 percent), more hospitalizations (29 percent versus 8 percent), and more serious adverse events (31 percent versus 9 percent) and also had no difference in lung function test changes. Participants randomly assigned to the triple- therapy arm also remained on their assigned treatment at a much lower rate (78 percent adherence versus 98 percent adherence). "Anyone on some combination of these medications with questions or concerns should consult with their health care provider and not simply stop taking the drugs," said Ganesh Raghu, M.D., professor of medicine at the University of Washington, Seattle and a co-chair of this IPF study. "It is important to realize that these results definitively apply only to patients with well-defined IPF and not to people taking a combination of these drugs for other lung diseases or conditions.”
Ever wonder how to manage your research articles or what medical apps are available for your mobile device? Come to a walk-up help session on Thursday, November 10th and librarians will answer these questions and many more. Drop by to hear about new resources and tools to manage research articles and format your references. Bring your iPad or smart phone for hands-on learning. For more information, contact Lynn Sette (737-2963) or Denise Hersey (785-6251) at the Medical Library.Date: Thursday, November 10Time: 10:00 a.m. to 3:00 p.m.Place: YNHH second floor octagonSponsored by: The Cushing/Whitney Medical Library
“100 Years of Child Study at Yale", is on display in the rotunda at the Cushing/Whitney Medical Library. The history of child development as a scientific field of study is primarily a story of the 20th century. The Yale Child Study Center stands as one of the few institutions – and the only one in a major University and School of Medicine – which has been a major source of leadership in the field from virtually the start of the field to the present.This achievement has several important roots – the position of the Center in a large research university, the support of Medical School administration, the devotion of faculty, and the presence of the senior leadership. An important component has been the capacity for long-term planning and program development, the continuity of senior leadership, and a commitment to the career development of young scholars, clinicians, and scientists. Also, in the 100 years of its existence, from 1911 to 2011 the Center has had only six directors, each of whom has helped guide the Center during distinctive epochs in the fields of child development and child and adolescent psychiatry.
This new resource is a collection of e-books; it consists of 50-100 page electronic books. Colloquium titles are dynamic presentations which synthesize an important research or development topic, written by scientists in the field for graduate students to researchers. Colloquium covers cell and molecular biology and biomedicine and offers added synthesis, analysis and depth than journal articles making it a useful resource for students and researchers examining advances in another discipline. Colloquium content is organized by series including Integrated Systems Physiology: From Molecule to Function to Disease. Developmental Biology Cell Biology of Medicine The Developing Brain Biotechnology Colloquium titles are available for digital download (PDF).
Harvey Cushing’s prized book collection contains several Arabic and Persian manuscripts. Faraḥ nāmah by al-Muṭahhar ibn Muḥammad Yazdī, copied in the 17th century from an 11th century manuscript, is a study of natural history, beautifully illuminated with detailed multicolored illustrations of animals, birds, plants, stones and humans. This manuscript, part of the Medical Historical Library’s collection, has recently been digitized by the Yale-SOAS Islamic Manuscript Gallery project. The note cards highlight six images from the manuscript which were selected by Medical Library staff. The sets of 6 cards are now available for purchase at the Circulation Desk in the Library. Stop by the Circulation Desk to view the cards and purchase a set to send to your family and friends!
]On October 28, 1810, the Connecticut Legislature approved a charter to create a medical school at Yale. The Medical Institution of Yale College, now Yale University School of Medicine, was the sixth medical school in the United States. From a single rented building with five faculty members and no hospital in the state of Connecticut, the Yale School of Medicine, in association with Yale-New Haven Hospital, has grown to become a world-famous center for teaching, research, and clinical practice. It was only in the twentieth century, after affiliation with the New Haven Hospital, the forming of departments, and the full-time system, that Yale became a leader in biomedical research and clinical care. However, the mission to educate medical students goes back to the beginning of the school’s history. This final Bicentennial exhibit focuses on the Medical School’s teaching mission over the past 200 years. The roughly chronological exhibit has two parts. Part I in the Medical Library rotunda traces the fundamental changes in medical education from an eight-month supplement to apprenticeship in 1813 to the establishment of the Yale System of Medical Education in 1925-1931. Part II, from the 1930s to the present, is located in the lobby outside the Library. The exhibit is supplemented by original historical photographs and engravings in the hallway of the Library. All materials on display, unless otherwise noted, are from the Historical Library. “200 Years of Medical Education” is curated by Toby A. Appel, former John R. Bumstead Librarian for Medical History. The exhibit goes to September 11. It is in the Medical Library rotunda, hallway, and lobby.
In 1836, the library of the U.S. Army Surgeon General consisted of a small collection of medical books on one shelf. Today, the National Library of Medicine (NLM) is the world’s largest biomedical library. With some 14 million items in more than 150 languages, it is the worldwide leader in trusted medical and health information and innovation. But this unique library is about much more than books. Every day it delivers trillions of bytes of data crucial to the lives of millions everywhere. NLM–designed databases and tools lead people to helpful medical literature and health information; help researchers study genes and their role in disease; provide emergency responders with critical information on hazardous substances, and much, much more. The Library is a leader in biomedical informatics, which is the use of computers and communications technology in biology, medicine, and health. NLM conducts and funds informatics research and trains future generations of scientists and information specialists. It plays an essential role in the development of electronic health records, health data standards, and the exchange of health information. In 1971, for example, NLM created Medline, an online database of references to the biomedical literature. Completely free access to Medline began in 1997 through PubMed, a new access system. Today, PubMed/Medline contains over 20 million references to articles published in more than 5,300 current biomedical journals from the U.S. and over 80 foreign countries. It is approaching one billion searches a year from users worldwide. NLM’s information services and research programs serve the nation and the world by supporting scientific discovery, clinical research, education, health care delivery, public health response, and the empowerment of people to improve personal health. The Library is committed to the innovative use of computing and communications to enhance effective public access to understanding and discovery in human health. - Dr. Donald A.B. Lindberg, M.D.,Director, National Library of Medicine
If you missed the premiere showing in the Harkness Auditorium in an early April, we invite you to come to the library to view the film about the School of Medicine, created in celebration of the school’s Bicentennial.The half-hour film, by Emmy Award–winning director and producer Karyl Evans, chronicles the rise of the School of Medicine from its origins as the Medical Institution of Yale College in 1810 to its current incarnation as one of the world’s major centers for biomedical research; clinical care; and the education of physicians, scientists, physician associates, and public health professionals. “Ancient Art, Modern Science” showcases recent advances in research and patient care at Yale and provides a glimpse of things to come as the school enters its third century.