Blogs

(by Rolando Garcia Milian and Terry Dagradi)

Last summer we invited Yale biomedical researchers (undergrads, graduate students, postdocs, faculty, associate researchers, etc.) to share results from their work where they felt the images produced in search of science crossed over to art.  We thank all of you who submitted and appreciate your willingness to share with the community. 

The images were reviewed by a committee including New Haven sculptor Gar Waterman, Sarah Fritchey (Curator / Gallery Director at Artspace New Haven), and Dr. Derek K. Toomre, Associate Professor of Cell Biology and Director of the YALE 'CINEMA’ Laboratory. Together, they selected many of the images currently on exhibit in the foyer of Cushing/Whitney Medical Library as well as the three 1st Honor awardees.

The 1st Honor Awardees are:

Marco Onorati, Department of Neurobiology

Neurons in a Dish, 2015

Juror comments: “Neuron: Good rendition, dreamy quality”  “The fantastic crystalline structure in the center of this composition is very powerful. The sense of pull and energy is so forceful that it almost suggests a big bang moment.”

(Click to view larger image)

Neurons differentiated in a dish from stem cells.  Microphotograph, fluorescence. 

Mustafa Khokha, Department of Pediatrics

Frog Head, Year: 2015

Juror comments: “Great composition and detail.”  “Just a cool thing, whatever it is”

(Click to view larger image)

Xenopus laevis tadpole (frog). Brain (green) and Actin (red) and nuclei (blue) View from the back of the head over the Imaged with Leica Sp8 Confocal by Helen Rankin Xenopus Cold Spring Harbor Course.

Kate Henderson, Department of Pathology

Stones Dreaming, 2013

Juror comment: “My favorite - love this one - fabulous color and pattern”

(Click to view larger image)

Abstract digital composition of microscopy endocrine images.

Image description: I create environments from natural elements to give people a sense of place, describing emotional essence and energy that connects us to each other and everything around us. My images both describe and celebrate the intrinsically aesthetic structure of the natural world and the ever-present duality in all things. I invite the viewer to see and feel the world both within us and around us, experiencing the macro vs microelements common to all.

Painting-with-cells is how I describe the cyto-Illusions series. I start by using microscope images of human cells and also images of abstraction “found” in nature. Through layering and manipulation techniques, I create an image that mirrors micro images on a macro level. On one level the images are a colorful abstraction that allow the viewer to freely explore and experience the image on their own. Many images are suggestive of a specific element such as water, but others are more environmentally placed. On another level the images are about the reality of nature; cells of disease, the growth structure of plants, and the patterns of light filtered through the leaves.

The Viewers’ Choice Award

This was determined by all those who voted (404 votes total) on an exhibition album created on the Medical Library Facebook page.

Laura Pappalardo – Department of Neurology

Astrocytes display robust intracellular calcium response in model of astrogliosis, 2013

(Click to view larger image)

Astrocytes, a non-neuronal type of cell in the brain and spinal cord, respond to central nervous system insult through the incompletely understood process of reactive astrogliosis, which is a hallmark in pathologies such as multiple sclerosis and spinal cord injury. While the ramifications of astrogliosis are debated, it is agreed that in its extreme forms, this process leads to the formation of a scar, which is long-lasting and can inhibit the regeneration of injured neurons. While the molecular drivers of astrogliosis are an area of active investigation, a clearer understanding is needed. Here, we show that after a scratch injury, there is a robust intracellular calcium response, which propagates through the syncytium of confluent astrocytes (red indicates high intracellular calcium). This calcium transient leads to downstream signaling that can regulate the astroglial response to injury. We are currently working to investigate the mechanisms behind this phenomenon, paying particular attention to voltage-gated sodium channels.

Color scale represents the ratio of fluorescent signals induced by 340 and 380 nm excitation in cells loaded with Fura-2 AM. Scale bar, 50 ╡m. In collaboration with Stephen Waxman, Joel Black, Mark Estacion, and Omar Samad.

The library will be closed Monday, January 18 in observance of the annual celebration of the life of Dr. Martin Luther King, Jr.  For service opportunities and other events, please visit http://mlk.yale.edu/.

Librarians at Yale have developed numerous online guides for Yale users.  Here at Yale, our guides can provide a number of things, including:

• Research guidance for a particular Yale course;
• Instructions on how to research a subject;
• Documentation for a research tool or service; or
• Instructions on accessing and using collections or resources.

You might find different guides of particular interest based on your role and field, for example:

• Basic Sciences Resources and Collections, for lab researchers
• Evidence-Based Clinical Practice Resources for clinicians, medical and nursing students, and others involved in delivering healthcare;
• Medical Education Services for faculty who teach at the School of Medicine; and
• NIH Public Access Policy, for researchers who receive NIH funding and the staff who support them.

Get started exploring our full list of guides in the field of medicine, or browse all Yale guides including on topics outside the health sciences. 

What is deafness? From a medical perspective, deafness is an audiological condition that might be resolved through hearing aids or cochlear implants. But from another perspective, to be Deaf (often spelled with a capital “D”) is to belong to a culture, with a shared language and identity. This exhibit explores how people have understood deaf communication and Deaf culture since the seventeenth century, with displays on the history of education, medical interventions, sign languages, and popular culture.

This exhibit runs Thursday, January 21, 2016 - Friday, April 1, 2016.

Additional events include:

For a list of upcoming events, please visit the exhibit page at http://library.medicine.yale.edu/historical/deaf.

(by Nathan Rupp and Melissa Grafe)

Nearly 900 Yale School of Medicine theses are now available through Yale University’s online institutional repository known as EliScholar. These include “current” theses published in the last decade that have come out of embargo as well as several YSM alumni theses published as far back as 1952. These theses document the rich research done by Yale’s medical students, and can provide a starting point for current medical students embarking on their projects.  We’re also pleased to make this part of our collection more openly accessible to researchers in general, as the print theses are stored in locked stacks at the Medical Library.  Current YSM students can browse this collection for examples of what a YSM thesis looks like.

For more information about accessing theses at the Medical Library, please see http://library.medicine.yale.edu/find/thesis.

If you are an alumnus and want your thesis digitized, complete this form and email it to Nathan Rupp at nathan.rupp@yale.edu.